Ethical issues in international biomedical research : a casebook /

Ethical issues in international biomedical research : a casebook /

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Bibliographic Details
Other Authors: Lavery, James V.
Format: Book
Language:English
Published: Oxford ; New York : Oxford University Press, 2007.
Subjects:
Human experimentation in medicine > Moral and ethical aspects > Case studies.
Human experimentation in medicine > Moral and ethical aspects > Cross-cultural studies.
Medicine > Research > Moral and ethical aspects > Case studies.
Medicine > Research > Moral and ethical aspects > Cross-cultural studies.
Human Experimentation > Ethics.
Biomedical Research > ethics.
Internationality.
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Table of Contents:
  • Collaborative partnership. Community involvement in biodiversity prospecting in Mexico. Selling genes. Sustainability of a fluoride varnish feasibility study in Nicaragua
  • Social value. Malarone testing in pregnant women in Thailand. Neglected diseases: incentives to conduct research in developing countries
  • Scientific validity. Evaluating home-based treatment strategies for neonatal sepsis in India. The limitations of knowledge. Controversy surrounding the scientific value of the VaxGen/Aventis (RV144) phase 3 vaccine trial in Thailand
  • Fair subject and community selection. Pharmaceutical research in developing countries. Trading genes for toothbrushes. Testing a phase 1 malaria vaccine
  • Favorable risk-benefit ratio. Ethical complications during an investigation of malaria infection in native Amazonian populations in western Brazil. Access to treatment for trial participants who become infected with HIV during the course of phase 1 trials of a preventive HIV vaccine in South Africa
  • Independent review. How independent is independent review? Which regulations offer subjects the best protection?
  • Informed consent. The challenge of informed consent in a genetic epidemiology study of Noma in rural Nigeria. Compensation for families who consent to research autopsy for their children in a study of malaria mortality in Malawi
  • Respect for enrolled subjects and study communities. A randomized trial of low-phytate corn for maternal-infant micronutrient deficiency in rural Guatemala. Obligations to participants harmed in the course of the N-9 multicenter vaginal microbicide trial in South Africa. Ethical challenges and controversy in a retrospective study of HIV-1 transmission in Uganda. Protecting subjects in a study of domestic violence in South Africa.

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