Solid-phase peptide synthesis
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2008.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/932/ Series |
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Table of Contents:
- Contents: Chemical structure of peptides
- Chemical peptide synthesis
- Classical solution synthesis
- Solid-phase peptide synthesis
- Chemistry of SPPS
- Automated solid-phase peptide synthesis
- Impact of SPPS
- Fundamentals of SPPS
- Synthesis takes place within the beads
- 'Super-elastic' swelling of peptide-resin beads
- Boc chemistry SPPS
- Fmoc chemistry SPPS
- 'Difficult' peptide sequences in SPPS
- Optimized solid-phase peptide synthesis
- Impact on SPPS of modern analytical methods
- Extensions of SPPS & applications of the solid-phase principle
- Scope and limitations of SPPS
- Impact of chemical ligation
- Total synthesis of human lysozyme.
Solid-phase peptide synthesis