Bioorganic studies of vision

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Bibliographic Details
Other Authors: Nakanishi, Koji (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology.
Subjects:
Online Access:https://hstalks.com/bs/934/
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Table of Contents:
  • Contents: Visual pigments
  • Visual chromophores
  • Activation of Rh and beta-AR
  • Retinal / vitamin A cycle
  • Selective capture of retinoid binding proteins
  • Photocrosslinking of chromophore to Rh
  • Tracking the chromophore / opsin interaction
  • Rhodopsin photocycle
  • Photoaffinity labelling
  • Chromophore confirmation in Rh
  • Transient 'dark activity' of 13-des-Me-retinal
  • Retinoids that form pigments
  • Photoaffinity study of rhodopsin: G-protein (transducin) interaction
  • Age-related macular degeneration
  • Age pigments or RPE lipofuscin
  • A2E flurophore
  • ATP binding cassette protein
  • Bilberry extract vs. blue-light induced A2E epoxidation.