Use of DNA pooling in large-scale association studies
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2004.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology I : fundamentals, theory, practice and latest developments.
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Subjects: | |
Online Access: | https://hstalks.com/bs/37/ Series |
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Table of Contents:
- Contents: Principles of DNA pooling
- The cost benefit
- Getting the quantification right
- SNaPshot
- Estimating and incorporating measurement error
- Consequences of differential amplification
- Pool construction vs. genotyping errors
- Determining optimal design
- Family designs
- Stratified designs
- Design for quantitative traits
- Methods for statistical analysis
- Case study: ADHD
- Approaches to haplotype analysis in DNA pooling
- Recommendations.