Segregation analysis

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Bibliographic Details
Other Authors: Cannings, C. (Christopher), 1942- (Speaker), Teare, Dawn (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2004.
Series:Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology I : fundamentals, theory, practice and latest developments.
Subjects:
Online Access:https://hstalks.com/bs/23/
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Table of Contents:
  • Contents: Components of segregation analysis
  • Maximum likelihood models
  • Peeling and MCMC
  • Estimating the segregation proportion
  • Ascertainment/sampling bias
  • Ascertainment correction
  • Segregation analysis for quantitative traits
  • Polygenic models
  • Heritability
  • Components of variance
  • Genetic variance: additive and dominance
  • Epistatic variance
  • Analysis of covariance
  • Mixed models
  • Liability and threshold models
  • The hypergeometric polygenic model
  • Regressive models
  • Penetrance functions
  • Survival models
  • Computer packages.