Nuclear receptors superfamily structural insights into function /
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. World of hormones : molecular and physiological insights.
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Subjects: | |
Online Access: | https://hstalks.com/bs/485/ Series |
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Table of Contents:
- Contents: Signal transduction and transcriptional regulation
- Cofactor binding and transcriptional activation
- The modular organization of nuclear hormone receptors
- The DNA binding domain
- The ligand binding domain
- Sequence/structure to function
- The oligomeric state
- Allosteric control through post-translational modifications
- Communication pathways in NRs
- Ligand binding: specificity and adaptability
- The retinoid receptors: RXR and RAR
- Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor
- Binding to coactivators and corepressors: the signature motifs
- Ligand dependent (de)activation: agonists and antagonists
- Estrogen receptor
- The vitamin D receptor.