Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2008.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis.
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Subjects: | |
Online Access: | https://hstalks.com/bs/806/ Series |
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Table of Contents:
- Contents: Schematic of elongation cycle
- Role of elongation factors EF-G and EF-Tu
- Molecular mimicry of elongation factors
- Binding positions of factors and tRNA during elongation cycle
- Process of tRNA selection
- Proofreading
- Role of bases A1492 and A1493
- GTP hydrolysis on EF-Tu
- tRNA as a molecular spring
- Translocation
- Intersubunit ratchet motion
- Induced fit
- FRET studies of ratchet motion
- Hybrid states of tRNA
- Role of GTP hydrolysis in translocation.