Translocation movement of tRNA and mRNA through the ribosome /

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Bibliographic Details
Other Authors: Noller, Harry F. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis.
Subjects:
Online Access:https://hstalks.com/bs/807/
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028 5 0 |a 1742  |b Henry Stewart Talks 
035 |a (UkLoHST)807 
035 |a (UkLU-K)AC000392183 
040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Noller, Harry F.  |4 spk  |9 112339 
245 1 0 |a Translocation  |h [electronic resource] :  |b movement of tRNA and mRNA through the ribosome /  |c Harry F. Noller. 
260 |a London :  |b Henry Stewart Talks,  |c 2008. 
300 |a 1 online resource (1 streaming video file (41 min.) :  |b color, sound). 
490 1 |a The mechanisms of ribosome function : insights into protein synthesis,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Ribosomes and translation -- Molecular composition of the ribosome -- Why is the ribosome so big? -- The mRNA channel in the 30S subunit -- Positions of tRNA in the A-, P- and E-sites -- Structural dynamics of the ribosome during translocation -- The hybrid states elongation cycle -- tRNA binding during its movement through the ribosome -- The 70S ribosome -- Distortion of tRNA structure by the ribosome -- The ratchet model -- Cryo-EM experiment -- Inferred relationship between ratcheting and hybrid states -- FRET changes -- Intersubunit movement -- Testing the ratchet model for translocation -- Translocation assay -- What defines the mechanism of translocation -- Sparsomycin -- The energetics of translocation -- E-site tRNA -- The ribosome is a molecular machine. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Protein Biosynthesis.  |9 112340 
650 2 |a Ribosomal Proteins.  |9 112341 
650 2 |a Ribosomes.  |9 112342 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Mechanisms of ribosome function : insights into protein synthesis.  |9 112343 
856 4 0 |u https://hstalks.com/bs/807/ 
856 4 2 |u https://hstalks.com/bs/p/285/  |3 Series 
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