The interaction of antibiotics with the large ribosomal subunit from Haloarcula Marismortui

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Bibliographic Details
Other Authors: Moore, Peter, 1939- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2008.
Series:Henry Stewart talks. Biomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis.
Subjects:
Online Access:https://hstalks.com/bs/811/
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MARC

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028 5 0 |a 1550  |b Henry Stewart Talks 
035 |a (UkLoHST)811 
035 |a (UkLU-K)AC000392172 
040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Moore, Peter,  |d 1939-  |4 spk  |9 111780 
245 1 4 |a The interaction of antibiotics with the large ribosomal subunit from Haloarcula Marismortui  |h [electronic resource] /  |c Peter Moore. 
260 |a London :  |b Henry Stewart Talks,  |c 2008. 
300 |a 1 online resource (1 streaming video file (49 min.) :  |b color, sound). 
490 1 |a The mechanisms of ribosome function : insights into protein synthesis,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Introduction to a paradox: how can a universally conserved cellular component be a target for pharmacologically useful antibiotics? -- Introduction to ribosome structure -- Antibiotic binding sites cluster in the ribosome -- The source of the species specificity of antibiotics that interact with the A-site cleft -- How macrolides interact with the ribosome -- The structural consequences of mutations that make ribosomes resistant to macrolides -- The toxicity of macrolides is not well understood -- 13-deoxytedanolide, a novel macrolide with novel species specificity that binds to a novel site in the ribosome. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Haloarcula Marismortui  |x drug effects.  |9 111781 
650 2 |a Protein Biosynthesis.  |9 111782 
650 2 |a Ribosomal Proteins.  |9 111783 
650 2 |a Ribosomes.  |9 111784 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Mechanisms of ribosome function : insights into protein synthesis.  |9 111785 
856 4 0 |u https://hstalks.com/bs/811/ 
856 4 2 |u https://hstalks.com/bs/p/285/  |3 Series 
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