Endoplasmic reticulum, protein synthesis and translocation machinery

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Bibliographic Details
Other Authors: Nicchitta, Christopher V. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Endoplasmic reticulum : fundamentals and role in disease.
Subjects:
Online Access:https://hstalks.com/bs/97/
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Table of Contents:
  • Contents: Protein sorting in the eukaryotic cell
  • The discovery of the secretory pathway
  • Overview discussion of the structure/function of the endoplasmic reticulum
  • Experimental protocols and landmark experiments leading to the discovery of protein translocation
  • The signal hypothesis
  • Signal sequence structure
  • Signal sequence recognition
  • SRP receptor and targeting to the ER
  • Mechanism of protein translocation and the protein translocation channel
  • Translational regulation on the ER
  • The unfolded protein response
  • mRNA partitioning in the cell
  • Are there alternative pathways for compartmentalizing protein synthesis?