Novel immunotherapeutic proteins immunoligand /

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Bibliographic Details
Other Authors: Strom, T. B. (Terry B.) (Speaker), Zheng, Xin Xiao (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances.
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Online Access:https://hstalks.com/bs/596/
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Table of Contents:
  • Contents: Potential advantages of mAB
  • Challenges for mAB
  • Antibody based therapeutic proteins
  • Attributes of immunoligands
  • Creation of Ig-based fusion proteins
  • Non-cytolytic IL-2/Fc fusion protein
  • Vaccine trial design
  • Creation of cytolytic IL-15R antagonist fusion protein
  • Application of immunoligand: immunogen for mAB production, to stain the cognate ligand, to identify cell surface cognate ligands via immunoprecipitation, to create long lived proteins to test the function of the targeting ligand in vivo and to modulate immune responses
  • Challenges for immunoligands.