Regulation of apoptosis lessons from Drosophila and their implications for human health and disease /

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Bibliographic Details
Other Authors: Steller, Hermann (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Apoptosis : fundamentals, pathways, clinical applications and role in disease.
Subjects:
Online Access:https://hstalks.com/bs/277/
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Table of Contents:
  • Contents: Many different signals influence apoptosis
  • "Gas" and "brake" model of apoptosis
  • Reaper, Hid and Grim
  • IAPs and cancer
  • Use of Drosophila
  • Ubiquitination and apoptosis
  • diap1
  • In proliferating tissues, damage induced cell death is compensated by extra growth of the neighboring cells
  • Evidence for the "active model" of compensatory proliferation
  • Regulation of caspase activation
  • Cytochrome c is required for effector caspase activation in Drosophila spermatids
  • Cyt-c-d and other apoptosome proteins are required for normal developmental apoptosis in the Drosophila retina
  • Generation of Sept4-null mice
  • Acquired characteristics of cancer cells.