Molecular epidemiology of lung cancer

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Bibliographic Details
Other Authors: Christiani, David C. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks.
Subjects:
Online Access:https://hstalks.com/bs/80/
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Table of Contents:
  • Contents: The influence of host factors on individual susceptibility to tobacco smoke
  • The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens
  • Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential
  • Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors
  • Polymorphisms in genes and the association of this with lung cancer development
  • The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet.