Molecular epidemiology of lung cancer
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks.
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Subjects: | |
Online Access: | https://hstalks.com/bs/80/ Series |
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Table of Contents:
- Contents: The influence of host factors on individual susceptibility to tobacco smoke
- The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens
- Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential
- Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors
- Polymorphisms in genes and the association of this with lung cancer development
- The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet.