Small interfering RNA induced transcriptional gene silencing in human cells
Saved in:
Other Authors: | |
---|---|
Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
|
Series: | Henry Stewart talks. Biomedical & life sciences collection. RNA interference : principles and applications.
|
Subjects: | |
Online Access: | https://hstalks.com/bs/651/ Series |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- Contents: How siRNAs mediate transcriptional gene silencing (TGS) in human cells
- Histone methylation
- Dependency on active RNA polymerase II mediated transcription
- siRNA-mediated TGS
- H3K9 and H3K27 methylation of the targeted EF1A promoter
- Nuclear specific delivery of the siRNA
- Antisense strand-specific siRNA-mediated TGS of EF1A
- Targeting of the U3 region of the HIV-1 LTR/promoter
- Antisense strand of siRNA EF2 interacts with FLAG-tagged DNMT3A and the tri-methylated H3K27 methyl mark
- siRNA mediated targeting of genomic regions
- RNA Pol-II function
- Transcriptional gene silencing in human cells.