Prion diseases
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2007.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/440/ Series |
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Table of Contents:
- Contents: Understanding the biophysical aspects of a disease of protein misfolding
- Structural studies of PrPc and PrPsc
- The development of synthetic mammalian prions and the proof of their infectivity and serial transmissibility
- Heterocyclic pharmacotherapies for prion disease
- Pyridinyl based therapies and structure based design
- Serendipitous discovery of acridines as anti-prion agents
- Bisacridines as potent inhibitors of prion replication in cell culture
- The relationship between the prion diseases and other diseases of protein misfolding.
Prion diseases