Epigenetically mediated gene silencing a companion to genetic alterations in driving tumorigenesis /
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| Other Authors: | |
|---|---|
| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2007.
|
| Series: | Henry Stewart talks. Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/124/ Series |
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| 008 | 080121s2007 enk|||||||||||s|||v|eng d | ||
| 028 | 5 | 0 | |a 1038 |b Henry Stewart Talks |
| 035 | |a (UkLoHST)124 | ||
| 035 | |a (UkLU-K)AC000390031 | ||
| 040 | |a UkLU-K |b eng |c UkLU-K | ||
| 100 | 1 | |a Baylin, Stephen B. |4 spk |9 109731 | |
| 245 | 1 | 0 | |a Epigenetically mediated gene silencing |h [electronic resource] : |b a companion to genetic alterations in driving tumorigenesis / |c Stephen Baylin. |
| 246 | 3 | |a Epigenetically mediated gene silencing : |b tumorigenesis | |
| 260 | |a London : |b Henry Stewart Talks, |c 2007. | ||
| 300 | |a 1 online resource (1 streaming video file (68 min.) : |b color, sound). | ||
| 490 | 1 | |a Epigenetics : concepts, theories, paradigms and mechanisms, |x 2056-452X | |
| 500 | |a Animated audio-visual presentation with synchronized narration. | ||
| 500 | |a Title from title frames. | ||
| 505 | 0 | |a Contents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer. | |
| 506 | |a Access restricted to subscribers. | ||
| 538 | |a Mode of access: World Wide Web. | ||
| 650 | 2 | |a Epigenesis, Genetic. |9 109732 | |
| 650 | 2 | |a Gene Expression Regulation, Neoplastic. |9 109733 | |
| 650 | 2 | |a Gene Silencing. |9 109734 | |
| 830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Epigenetics : concepts, theories, paradigms and mechanisms. |9 109735 | |
| 856 | 4 | 0 | |u https://hstalks.com/bs/124/ |
| 856 | 4 | 2 | |u https://hstalks.com/bs/p/18/ |3 Series |
| 999 | |c 215800 |d 215799 | ||
Epigenetically mediated gene silencing a companion to genetic alterations in driving tumorigenesis /