RNAi and heterochromatin in plants and fission yeast
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Other Authors: | |
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.
Henry Stewart talks. Biomedical & life sciences collection. RNA interference : principles and applications. |
Subjects: | |
Online Access: | https://hstalks.com/bs/112/ Series (Epigenetics) Series (RNA interference) |
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028 | 5 | 0 | |a 1026 |b Henry Stewart Talks |
035 | |a (UkLoHST)112 | ||
035 | |a (UkLU-K)AC000390080 | ||
040 | |a UkLU-K |b eng |c UkLU-K | ||
100 | 1 | |a Martienssen, Robert A. |4 spk |9 109663 | |
245 | 1 | 0 | |a RNAi and heterochromatin in plants and fission yeast |h [electronic resource] / |c Robert Martienssen. |
260 | |a London : |b Henry Stewart Talks, |c 2007. | ||
300 | |a 1 online resource (1 streaming video file (41 min.) : |b color, sound). | ||
490 | 1 | |a Epigenetics : concepts, theories, paradigms and mechanisms, |x 2056-452X | |
490 | 1 | |a RNA interference : principles and applications, |x 2056-452X | |
500 | |a Animated audio-visual presentation with synchronized narration. | ||
500 | |a Title from title frames. | ||
505 | 0 | |a Contents: Heterochromatin is composed of transposable elements (TEs) and related repeats -- heterochromatic gene silencing and TE-mediated silencing are related and may be important in large genomes -- tiling microarrays can be used to examine heterochromatic transcripts as well as DNA and histone modification -- small interfering RNA (siRNA) corresponds to transposons and repeats -- in plants TE siRNA depend on DNA methyltransferase MET1 and the SWI/SNF ATPase DDM1 which silence TEs via DNA and histone H3 lysine-9 (H3K9) methylation -- in fission yeast and plants centromeric repeats are transcribed on one strand but rapidly turned over by RNA interference (RNAi) -- RNAi of centromeric transcripts is required for transcriptional silencing of reporter genes -- RNA polymerase II, the Argonaute (RITS) and RNA dependent RNA polymerase (RDRC) complexes are associated with heterochromatin and required for silencing -- H3K9me2 depends on RNAi and on the Rik1-Clr4 complex -- Clr4 is the histone H3K9 dimethyltransferase -- Rik1 resembles both DNA and RNA binding proteins and is required for RNAi along with Clr4 -- LTR retrotransposon silencing depends on histone deacetylation and silences pericentromeric repeats in Arabidopsis in addition to RNAi. | |
506 | |a Access restricted to subscribers. | ||
538 | |a Mode of access: World Wide Web. | ||
650 | 2 | |a Epigenesis, Genetic. |9 109664 | |
650 | 2 | |a Heterochromatin. |9 109665 | |
650 | 2 | |a Plants. |9 109666 | |
650 | 2 | |a RNA Interference. |9 109667 | |
650 | 2 | |a Schizosaccharomyces. |9 109668 | |
830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Epigenetics : concepts, theories, paradigms and mechanisms. |9 109669 | |
830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p RNA interference : principles and applications. |9 109670 | |
856 | 4 | 0 | |u https://hstalks.com/bs/112/ |
856 | 4 | 2 | |u https://hstalks.com/bs/p/18/ |3 Series (Epigenetics) |
856 | 4 | 2 | |u https://hstalks.com/bs/p/37/ |3 Series (RNA interference) |
999 | |c 215793 |d 215792 |