A historical perspective on ideas on X-chromosome inactivation

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Bibliographic Details
Other Authors: Lyon, Mary F. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.
Subjects:
Online Access:https://hstalks.com/bs/107/
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028 5 0 |a 1021  |b Henry Stewart Talks 
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100 1 |a Lyon, Mary F.  |4 spk  |9 109632 
245 1 2 |a A historical perspective on ideas on X-chromosome inactivation  |h [electronic resource] /  |c Mary Lyon. 
260 |a London :  |b Henry Stewart Talks,  |c 2007. 
300 |a 1 online resource (1 streaming video file (34 min.) :  |b color, sound). 
490 1 |a Epigenetics : concepts, theories, paradigms and mechanisms,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: The phenomenon of X-chromosome inactivation in female mammals -- X-chromosome inactivation as a dosage compensation mechanism for equalising the dosage of X-linked gene products in XY males and XX females in somatic cells -- inactivity of either the maternal or paternal X-chromosome in different cells in eutherian mammals -- preferential inactivation of paternal X in the placenta of mice and in all cells of marsupials -- initiation of the process from an X-inactivation centre -- discovery of the key gene, Xist -- the concept of initiation and maintenance of X-inactivation as separate processes -- histone modifications and methylation of CpG islands as maintenance mechanisms -- inactivation in autosomal and X-chromosomal DNA -- LINE1s as booster elements on the X-chromosome. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Epigenesis, Genetic.  |9 109633 
650 2 |a X Chromosome Inactivation.  |9 109634 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Epigenetics : concepts, theories, paradigms and mechanisms.  |9 109635 
856 4 0 |u https://hstalks.com/bs/107/ 
856 4 2 |u https://hstalks.com/bs/p/18/  |3 Series 
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