Plasmacytoid dendritic cells sensing nucleic acids in viral infection and autoimmunity /
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| Other Authors: | |
|---|---|
| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2009.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/1289/ Series |
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| 028 | 5 | 0 | |a 2077 |b Henry Stewart Talks |
| 035 | |a (UkLoHST)1289 | ||
| 035 | |a (UkLU-K)001155622 | ||
| 040 | |a UkLU-K |b eng |c UkLU-K | ||
| 100 | 1 | |a Liu, Yong-Jun, |u (University of Texas MD Anderson Cancer Center, USA) |4 spk |9 109504 | |
| 245 | 1 | 0 | |a Plasmacytoid dendritic cells |h [electronic resource] : |b sensing nucleic acids in viral infection and autoimmunity / |c Yong-Jun Liu. |
| 260 | |a London : |b Henry Stewart Talks, |c 2009. | ||
| 300 | |a 1 online resource (1 streaming video file (25 min.) : |b color, sound). | ||
| 490 | 1 | |a Innate immunity : host recognition and response in health and disease, |x 2056-452X | |
| 500 | |a Animated audio-visual presentation with synchonized narration. | ||
| 500 | |a Title from title frames. | ||
| 505 | 0 | |a Contents: Plasmacytoid dendritic cells (pDCs) are important mediators of antiviral immunity through their ability to produce large amounts of type I interferons (IFNs) on viral infection -- This function of pDCs is linked to their expression of Toll-like receptor 7 (TLR7) and TLR9, which sense viral nucleic acids within the early endosomes -- Exclusion of self nucleic acids from TLR-containing early endosomes normally prevents pDC responses to them -- In some autoimmune diseases, self nucleic acids can be modified by host factors and gain entrance to pDC endosomes, where they activate TLR signaling -- Several pDC receptors negatively regulate type I IFN responses by pDCs during viral infection and for normal homeostasis. | |
| 506 | |a Access restricted to subscribers. | ||
| 538 | |a Mode of access: World Wide Web. | ||
| 650 | 2 | |a Immunity, Innate. |9 109505 | |
| 830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Innate immunity : host recognition and response in health and disease. |9 109506 | |
| 856 | 4 | 0 | |u https://hstalks.com/bs/1289/ |
| 856 | 4 | 2 | |u https://hstalks.com/bs/p/437/ |3 Series |
| 999 | |c 215756 |d 215755 | ||
Plasmacytoid dendritic cells sensing nucleic acids in viral infection and autoimmunity /