Receptor identification for alarmins and DAMPs

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Bibliographic Details
Other Authors: Oppenheim, Joost J., 1934- (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2011.
Series:Henry Stewart talks. Biomedical & life sciences collection. Cytokines.
Subjects:
Online Access:https://hstalks.com/bs/2156/
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Table of Contents:
  • Contents: Definition of Alarmins and Damps
  • History of discovery that antimicrobial peptides such as Beta Defensins recruit and activate immune cells engaged in host defense
  • Identification of other antimicrobials such as granulysin and nuclear binding factors, e.g. HMGN1, as also acting as alarmins that activate receptors on host cells
  • Proposal to use some alarmins as vaccine adjuvants.