Receptor identification for alarmins and DAMPs
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2011.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Cytokines.
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Subjects: | |
Online Access: | https://hstalks.com/bs/2156/ Series |
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Table of Contents:
- Contents: Definition of Alarmins and Damps
- History of discovery that antimicrobial peptides such as Beta Defensins recruit and activate immune cells engaged in host defense
- Identification of other antimicrobials such as granulysin and nuclear binding factors, e.g. HMGN1, as also acting as alarmins that activate receptors on host cells
- Proposal to use some alarmins as vaccine adjuvants.