Interleukin-6 back to the future /
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| Other Authors: | |
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| Format: | Electronic Video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2011.
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| Series: | Henry Stewart talks. Biomedical & life sciences collection. Cytokines.
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| Subjects: | |
| Online Access: | https://hstalks.com/bs/2148/ Series |
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Table of Contents:
- Contents: IL-6 is a pleiotropic proinflammatory cytokine
- Its overproduction is involved in inflammatory autoimmune diseases including rheumatoid arthritis
- Blocking of IL-6 signals by anti-IL6 receptor antibody (Tocilizumab) shows therapeutic effect on various autoimmune diseases
- Tocilizumab exerts its effect by inhibiting the induction of a helper T cell subset (TH17)
- Aryl-hydrocarbon receptor (Ahr) is one of the essential molecule for the IL-6 mediated induction of TH17 cells.
Interleukin-6 back to the future /