Management of MDR and XDR TB
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2014.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Respiratory infection.
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Subjects: | |
Online Access: | https://hstalks.com/bs/2809/ Series |
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Table of Contents:
- Contents: Management of multi drug resistance (MDR) and extensive drug resistance (XDR) TB
- Management of TB before era of drug treatment
- Surgery for TB
- Drug treatment was introduced from 1943-1963
- Rifampicin (1963)
- Timeline: discovery of drugs for TB
- Emergence of totally drug resistant TB
- Epidemiology
- Outcomes of MDR-TB treatment
- Survival curve of HIV patients with XDR TB
- Current drug treatment
- Treatment outcome in several cohorts
- Death rates in several cohorts
- Current approach for treatment of MDR/XDR TB
- WHO's programmatic management of DR TB
- Treatment recommendations
- Group 1: oral first-line agents
- Group 2: fluoroquinolones
- Group 3: injectables
- Group 4: less-effective anti-TB drugs
- Group 5: less-effective or clinical data sparse drugs
- Future drug treatment
- New compounds
- Bedaquiline (TMC207)
- The nitroimidazoles
- Thioridazine
- NC-001 (PA-824, moxifloxacine, PZA)
- Dreams and realities for the future of TB treatment.