Rheumatic fever a model of a post-infectious autoimmune disease /

Saved in:
Bibliographic Details
Other Authors: Kalil, Jorge (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2019.
Series:Henry Stewart talks. Biomedical & life sciences collection. Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies.
Subjects:
Online Access:https://hstalks.com/bs/214/
Series
Tags: Add Tag
No Tags, Be the first to tag this record!
Table of Contents:
  • Contents: Autoimmunity in humans
  • Infectious agents can induce breakage of tolerance to self to trigger & maintain autoimmune disease
  • Rheumatic Fever & Rheumatic Heart Disease (RHD) as paradigms of post-infectious autoimmune disease
  • Medical & sociological importance of RHD
  • Genes involved in susceptibility
  • T cell mediated autoimmunity
  • Molecular mimicry
  • Role of Th1 cells in human autoimmunity
  • How chemokines can drive disease to different site
  • Identification of autoimmune vs. anti-infection triggering epitopes
  • Vaccine development to avoid infections & autoimmune disease.