Rheumatic fever a model of a post-infectious autoimmune disease /
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2019.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies.
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Subjects: | |
Online Access: | https://hstalks.com/bs/214/ Series |
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Table of Contents:
- Contents: Autoimmunity in humans
- Infectious agents can induce breakage of tolerance to self to trigger & maintain autoimmune disease
- Rheumatic Fever & Rheumatic Heart Disease (RHD) as paradigms of post-infectious autoimmune disease
- Medical & sociological importance of RHD
- Genes involved in susceptibility
- T cell mediated autoimmunity
- Molecular mimicry
- Role of Th1 cells in human autoimmunity
- How chemokines can drive disease to different site
- Identification of autoimmune vs. anti-infection triggering epitopes
- Vaccine development to avoid infections & autoimmune disease.