Autophagy dysfunction in lysosomal storage disorders

Autophagy dysfunction in lysosomal storage disorders

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Bibliographic Details
Other Authors: Settembre, Carmine (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2019.
Series:Henry Stewart talks. Biomedical & life sciences collection. Autophagy and lysosomal storage diseases.
Subjects:
Cell death.
Lysosomal storage disorders.
Lysosomes.
Autophagy > drug effects.
Autophagy > physiology.
Lysosomal Storage Diseases.
Lysosomes > metabolism.
Mechanistic Target of Rapamycin Complex 1.
Online Access:https://hstalks.com/bs/4103/
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Table of Contents:
  • Contents: Overview of the lysosome and autophagy
  • Lysosomal storage disorders (LSDs)
  • Lysosomal vacuolization
  • Accumulation of LC3+ vesicles
  • Studying co-localization of Lamp1 with LC3 and p62
  • LC3-tandem assay to study AV-lysosome fusion
  • mTORC1 inhibitors and AV-lysosome fusion
  • Pharmacological modulation of autophagy.

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