Arginase and nitric oxide

Saved in:
Bibliographic Details
Other Authors: Murray, Peter J., Ph. D. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2009.
Series:Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease.
Subjects:
Online Access:https://hstalks.com/bs/1301/
Series
Tags: Add Tag
No Tags, Be the first to tag this record!
Table of Contents:
  • Contents: Catabolism of arginine to downstream substrates
  • Catabolism of arginine in macrophages
  • Nitric oxide production
  • Control of iNOS at the transcriptional level
  • Role of nitric oxide in immunity to intracellular pathogens with a focus on mycobacterial disease
  • Structure of arginases
  • Transcriptional control of arginase 1 in the liver vs. macrophages
  • Arginases can suppress nitric oxide production by substrate depletion
  • Pathogens use many mechanisms to regulate nitric oxide
  • Arginases and alternatively-activated macrophages (AAMs)
  • Schistosome infection as an example of AAM function
  • AAMs and arginases
  • Arginase inhibition by small molecules
  • Outstanding questions.