Arginase and nitric oxide
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2009.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease.
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Subjects: | |
Online Access: | https://hstalks.com/bs/1301/ Series |
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Table of Contents:
- Contents: Catabolism of arginine to downstream substrates
- Catabolism of arginine in macrophages
- Nitric oxide production
- Control of iNOS at the transcriptional level
- Role of nitric oxide in immunity to intracellular pathogens with a focus on mycobacterial disease
- Structure of arginases
- Transcriptional control of arginase 1 in the liver vs. macrophages
- Arginases can suppress nitric oxide production by substrate depletion
- Pathogens use many mechanisms to regulate nitric oxide
- Arginases and alternatively-activated macrophages (AAMs)
- Schistosome infection as an example of AAM function
- AAMs and arginases
- Arginase inhibition by small molecules
- Outstanding questions.