Molecular biology of ryanodine receptors
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Format: | Electronic Video |
Language: | English |
Published: |
London :
Henry Stewart Talks,
2007.
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Series: | Henry Stewart talks. Biomedical & life sciences collection. Calcium signaling I.
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Subjects: | |
Online Access: | https://hstalks.com/bs/405/ Series |
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Table of Contents:
- Contents: Molecular cloning of RyR
- The identification of functional domains
- RyR channel structure
- Channel regulation by: a) inter-RyR interaction, b) divalent cations and c) protein:protein interactions
- The role of leucine zippers in assembling the 'macromolecular complex'
- Defective protein:protein interactions in cardiac disease
- Genetic basis of RyR dysfunction
- Identification of mutations in cardiac RyR
- Functional characterization of RyR mutations
- Investigating interdomain interactions using state-of-the-art imaging tools
- Pathological defects in channel stability.