Analysis of SNP haplotypes

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Bibliographic Details
Other Authors: Palmer, Lyle (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks.
Subjects:
Online Access:https://hstalks.com/bs/77/
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Table of Contents:
  • Contents: Phenotype-genotype association
  • Linkage disequilibrium maps and allelic association
  • What is linkage disequilibrium?
  • The role of linkage disequilibrium in facilitating allelic association
  • What is a haplotype?
  • The importance of haplotypes
  • Haplotype tagging
  • The missing phase information problem
  • Haplotype determination options
  • Statistical estimation of haplotypes
  • General framework for case-control studies using haplotypes
  • Haplotype estimation and permutation testing
  • Statistical challenges
  • Software packages.