RNAi and heterochromatin in plants and fission yeast

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Bibliographic Details
Other Authors: Martienssen, Robert A. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2007.
Series:Henry Stewart talks. Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.
Henry Stewart talks. Biomedical & life sciences collection. RNA interference : principles and applications.
Subjects:
Online Access:https://hstalks.com/bs/112/
Series (Epigenetics)
Series (RNA interference)
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028 5 0 |a 1026  |b Henry Stewart Talks 
035 |a (UkLoHST)112 
035 |a (UkLU-K)AC000390080 
040 |a UkLU-K  |b eng  |c UkLU-K 
100 1 |a Martienssen, Robert A.  |4 spk 
245 1 0 |a RNAi and heterochromatin in plants and fission yeast  |h [electronic resource] /  |c Robert Martienssen. 
260 |a London :  |b Henry Stewart Talks,  |c 2007. 
300 |a 1 online resource (1 streaming video file (41 min.) :  |b color, sound). 
490 1 |a Epigenetics : concepts, theories, paradigms and mechanisms,  |x 2056-452X 
490 1 |a RNA interference : principles and applications,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Heterochromatin is composed of transposable elements (TEs) and related repeats -- heterochromatic gene silencing and TE-mediated silencing are related and may be important in large genomes -- tiling microarrays can be used to examine heterochromatic transcripts as well as DNA and histone modification -- small interfering RNA (siRNA) corresponds to transposons and repeats -- in plants TE siRNA depend on DNA methyltransferase MET1 and the SWI/SNF ATPase DDM1 which silence TEs via DNA and histone H3 lysine-9 (H3K9) methylation -- in fission yeast and plants centromeric repeats are transcribed on one strand but rapidly turned over by RNA interference (RNAi) -- RNAi of centromeric transcripts is required for transcriptional silencing of reporter genes -- RNA polymerase II, the Argonaute (RITS) and RNA dependent RNA polymerase (RDRC) complexes are associated with heterochromatin and required for silencing -- H3K9me2 depends on RNAi and on the Rik1-Clr4 complex -- Clr4 is the histone H3K9 dimethyltransferase -- Rik1 resembles both DNA and RNA binding proteins and is required for RNAi along with Clr4 -- LTR retrotransposon silencing depends on histone deacetylation and silences pericentromeric repeats in Arabidopsis in addition to RNAi. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Epigenesis, Genetic. 
650 2 |a Heterochromatin. 
650 2 |a Plants. 
650 2 |a RNA Interference. 
650 2 |a Schizosaccharomyces. 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Epigenetics : concepts, theories, paradigms and mechanisms. 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p RNA interference : principles and applications. 
856 4 0 |u https://hstalks.com/bs/112/ 
856 4 2 |u https://hstalks.com/bs/p/18/  |3 Series (Epigenetics) 
856 4 2 |u https://hstalks.com/bs/p/37/  |3 Series (RNA interference) 
999 |c 202006  |d 202006