Drug-induced liver disease an update for 2010 /

Drug-induced liver disease an update for 2010 /

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Bibliographic Details
Other Authors: Lewis, James H. (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2011.
Series:Henry Stewart talks. Biomedical & life sciences collection. Gastroenterology and hepatology.
Subjects:
Drug-Induced Liver Injury.
Gastroenterology.
Online Access:https://hstalks.com/bs/1916/
Series
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028 5 0 |a 2673  |b Henry Stewart Talks 
035 |a (UkLoHST)1916 
040 |a UkLoHST  |b eng  |c UkLoHST 
100 1 |a Lewis, James H.  |4 spk 
245 1 0 |a Drug-induced liver disease  |h [electronic resource] :  |b an update for 2010 /  |c James H. Lewis. 
260 |a London :  |b Henry Stewart Talks,  |c 2011. 
300 |a 1 online resource (1 streaming video file (76 min.) :  |b color, sound). 
490 1 |a Gastroenterology and hepatology : pathophysiology, presentation, diagnosis and management,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: DILD overview -- Pathology of DILD -- Incidence of DILI -- Spectrum of DILI -- Hepatic adverse event nomenclature: liver injury -- Causes of acute liver failure -- Biochemical patterns of liver injury -- Clinical features of acute hepatocellular DILD -- Cholestatic DILI -- Drugs associated with chronic autoimmune type hepatitis -- Drugs associated with hepatic fibrosis/cirrhosis -- Drug-induced steatohepatitis -- Miscellaneous forms of chronic DILD -- Prevalence of hepatic enzyme elevations with various drugs -- Possible mechanisms of drug adaptation (drug tolerance) -- Drugs that have caused fulminant hepatic failure -- FDA stopping rule for liver injury in drug development -- Mortality from acute DILD -- Hy's law -- Causes of drug induced ALF leading to liver transplant -- Major regulatory actions due to DILI -- Drug related and idiosyncratic mechanisms of cellular injury in DILI -- Drug metabolism and risk of DILI -- Acetaminophen association with DILI -- Host risk factors for DILD -- Possible genetic predisposition to DILD -- Alcohol and other agents that affect drug hepatotoxicity -- Medicating patients with underlying liver disease -- The importance of accurately diagnosing DILI -- Improving the causality assessment process using scoring systems -- Preventing drug induced liver disease -- Treating DILD -- Herbal agents (problems and use) -- DILI risk vs. benefit considerations -- Future directions in DILD. 
506 |a Access restricted to subscribers. 
538 |a Mode of access: World Wide Web. 
650 2 |a Drug-Induced Liver Injury. 
650 2 |a Gastroenterology. 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection.  |p Gastroenterology and hepatology. 
856 4 0 |u https://hstalks.com/bs/1916/ 
856 4 2 |u https://hstalks.com/bs/p/532/  |3 Series 
999 |c 201819  |d 201819 

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