Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1
Saved in:
| 其他作者: | |
|---|---|
| 格式: | 電子 影片 |
| 語言: | English |
| 出版: |
London :
Henry Stewart Talks,
2014.
|
| 叢編: | Henry Stewart talks. Biomedical & life sciences collection. Antivirals.
|
| 主題: | |
| 在線閱讀: | https://hstalks.com/bs/2659/ Series |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
添加標簽 MARC
| LEADER | 00000ngm a2200000 a 4500 | ||
|---|---|---|---|
| 001 | HST3250 | ||
| 003 | UkLoHST | ||
| 006 | m c | ||
| 007 | cr|cna|||a|||| | ||
| 007 | vz|czazum | ||
| 008 | 140422s2014 enk|||||||||||s|||v|eng d | ||
| 028 | 5 | 0 | |a 3250 |b Henry Stewart Talks |
| 035 | |a (UkLoHST)2659 | ||
| 040 | |a UkLoHST |b eng |c UkLoHST | ||
| 100 | 1 | |a Rossi, John, |u (Beckman Research Institute of the City of Hope, USA) |4 spk | |
| 245 | 1 | 0 | |a Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1 |h [electronic resource] / |c John Rossi. |
| 260 | |a London : |b Henry Stewart Talks, |c 2014. | ||
| 300 | |a 1 online resource (1 streaming video file (38 min.) : |b color, sound). | ||
| 490 | 1 | |a Antivirals : latest developments and future progress, |x 2056-452X | |
| 500 | |a Animated audio-visual presentation with synchronized narration. | ||
| 500 | |a Title from title frames. | ||
| 505 | 0 | |a Contents: Systemic RNA interference (RNAi): Therapeutics for the treatment of HIV-1 -- HIV life cycle -- Typical Course of HIV infection -- Why do we need new HIV drugs? -- Major goals of anti-HIV therapies -- Combinatorial RNA based therapy for HIV -- Applying RNAi for the treatment of human diseases -- treat HIV infection by systemic delivery of small RNAs -- Aptamers -- Chimeric-siRNA aptamer uptake into gp120 expressing cells -- Aptamer-targeted RNA interference for HIV-1 therapy -- Aptamer and aptamer chimera mediated inhibition of HIV-1 -- Small animal model for studying anti-HIV RNAi based therapies -- Both aptamer and aptamer chimera inhibit HIV infection -Aptamer and chimeric aptamer-siRNA prevent CD4+ cell decline -- Aptamer and dsiRNAS effect on viral load -- Flexible PAMAM dendrimers with a triethanolamine core -- Dendrimers plus siRNAs form nanoparticles, protect siRNA from degradation and deliver siRNAs to T-lymphocytes -- G5 dendrimer delivered siRNAs down regulate target mRNAs in vitro -- Multiplex siRNAs for HIV-1 treatment -- In vivo analyses of G5 dendrimer delivered siRNAs -- Reductions in HIV loads following dendrimer siRNA injections -- Dendrimer-siRNA complexes protect HIV infected RAG-hu mice from CD4 T cell loss -- Bio distribution of G5 dendrimer siRNAs. | |
| 506 | |a Access restricted to subscribers. | ||
| 538 | |a Mode of access: World Wide Web. | ||
| 650 | 0 | |a Antiviral agents. | |
| 650 | 0 | |a Gene therapy. | |
| 650 | 0 | |a HIV infections |x Treatment. | |
| 650 | 0 | |a Small interfering RNA |x Therapeutic use. | |
| 650 | 2 | |a Acquired Immunodeficiency Syndrome |x drug therapy. | |
| 650 | 2 | |a Anti-HIV Agents |x therapeutic use. | |
| 650 | 2 | |a Genetic Therapy. | |
| 650 | 2 | |a HIV Infections |x drug therapy. | |
| 650 | 2 | |a HIV-1 |x drug effects. | |
| 650 | 2 | |a Molecular Targeted Therapy. | |
| 650 | 2 | |a RNA Interference. | |
| 650 | 2 | |a RNA, Small Interfering |x therapeutic use. | |
| 830 | 0 | |a Henry Stewart talks. |p Biomedical & life sciences collection. |p Antivirals. | |
| 856 | 4 | 0 | |u https://hstalks.com/bs/2659/ |
| 856 | 4 | 2 | |u https://hstalks.com/bs/p/613/ |3 Series |
| 999 | |c 201298 |d 201298 | ||
Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1