Genetic abnormalities in acute lymphoblastic leukemia

Genetic abnormalities in acute lymphoblastic leukemia

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Bibliographic Details
Other Authors: Pui, Ching-Hon (Speaker)
Format: Electronic Video
Language:English
Published: London : Henry Stewart Talks, 2015.
Series:Henry Stewart talks. Biomedical & life sciences collection. Cancer genetics.
Subjects:
Cancer > Genetic aspects.
Genetic disorders.
Lymphoblastic leukemia.
Chromosome Aberrations.
Genome-Wide Association Study.
Neoplasms > genetics.
Polymorphism, Genetic.
Precursor Cell Lymphoblastic Leukemia-Lymphoma > drug therapy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma > genetics.
Online Access:https://hstalks.com/bs/3138/
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Table of Contents:
  • Contents: Somatic genetic abnormalities
  • Genetic classification
  • Leukemogenesis
  • Heterogeneity due to age of presentation, differences in cooperative mutations and target cells undergoing malignant transformation
  • Genome-wide analysis disclosed novel genetic subtypes, driver mutations and targetable genetic lesions
  • Germline polymorphisms and mutations affecting cancer susceptibility, treatment response and toxicity
  • Precision medicine based on somatic and germline genetics.

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