The Gene Ontology Handbook

This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers...

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Chi tiết về thư mục
Tác giả của công ty: SpringerLink (Online service)
Tác giả khác: Dessimoz, Christophe (Biên tập viên), Škunca, Nives (Biên tập viên)
Định dạng: Điện tử eBook
Ngôn ngữ:Tiếng Anh
Được phát hành: New York, NY : Springer New York : Imprint: Humana Press, 2017.
Loạt:Methods in Molecular Biology, 1446
Những chủ đề:
Truy cập trực tuyến:http://dx.doi.org/10.1007/978-1-4939-3743-1
http://www.springerprotocols.com/doiresolver?genre=book&pid=10.1007/978-1-4939-3743-1
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Mục lục:
  • Primer on Ontologies
  • The Gene Ontology and the Meaning of Biological Function
  • Primer on the Gene Ontology
  • Best Practices in Manual Annotation with the Gene Ontology
  • Computational Methods for Annotation Transfers from Sequence
  • Text Mining to Support Gene Ontology Curation and Vice Versa
  • How Does the Scientific Community Contribute to Gene Ontology?
  • Evaluating Computational Gene Ontology Annotations
  • Evaluating Functional Annotations of Enzymes Using the Gene Ontology
  • Community-Based Evaluation of Computational Function Prediction
  • Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools
  • Semantic Similarity in the Gene Ontology
  • Gene-Category Analysis
  • Gene Ontology: Pitfalls, Biases, and Remedies
  • Visualizing GO Annotations
  • A Gene Ontology Tutorial in Python
  • Annotation Extensions
  • The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations
  • Complementary Sources of Protein Functional Information: The Far Side of GO
  • Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes
  • The Vision and Challenges of the Gene Ontology.