Drug repositioning bringing new life to shelved assets and existing drugs /

में बचाया:
ग्रंथसूची विवरण
निगमित लेखक: ebrary, Inc
अन्य लेखक: Barratt, Michael J., Frail, Donald
स्वरूप: इलेक्ट्रोनिक ई-पुस्तक
भाषा:अंग्रेज़ी
प्रकाशित: Hoboken : John Wiley & Sons, c2012.
विषय:
ऑनलाइन पहुंच:An electronic book accessible through the World Wide Web; click to view
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विषय - सूची:
  • Drug repositioning : the business case and current strategies to repurpose shelved candidates and marketed drugs / John Arrowsmith and Richard Harrison
  • Opportunities and challenges associated with developing additional indications for clinical development candidates and marketed drugs / Donald Frail and Michael Barratt
  • Clinical and operational considerations in repositioning marketed drugs and drug candidates / Damian O'Connell, David Sequeira, and Maria Miller
  • Regulatory considerations and strategies for drug repositioning / Ken Phelps
  • Computational and bioinformatic strategies for drug repositioning / Richard Mazzarella and Craig Webb
  • Mining scientific and clinical databases to identify novel uses for existing drugs / Christos Andronis ... [et al.]
  • Predicting the polypharmacology of drugs : identifying new uses through chemoinformatics, structural informatics and molecular modeling based approaches / Li Xie ... [et al.]
  • Systematic phenotypic screening for novel synergistic combinations: a new paradigm for repositioning existing drugs / Margaret Lee
  • Phenotypic in vivo screening to identify new, unpredicted indications for existing drugs and drug candidates / Michael Saporito, Christopher Lipinski, and Andrew Reaume
  • Old drugs yield new discoveries : examples from the prodrug, chiral switch and site-selective deuteration strategies / Adam Morgan ... [et al.]
  • Repurposing drugs for tropical diseases : case studies and open-source screening initiatives / Curtis Chong
  • Drug repositioning efforts by non-profit foundations
  • Business development strategies in the repositioning industry / Aris Persidis and Elizabeth Stark
  • A case study in drug repositioning : Sosei / Akinori Mochizuki and Makiko Aoyama.