Drug repositioning bringing new life to shelved assets and existing drugs /
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|---|---|
| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken :
John Wiley & Sons,
c2012.
|
| Subjects: | |
| Online Access: | An electronic book accessible through the World Wide Web; click to view |
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| 005 | 20171002062412.0 | ||
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| 007 | cr cn||||||||| | ||
| 008 | 111025s2012 njua sb 001 0 eng d | ||
| 010 | |z 2011044253 | ||
| 020 | |z 9780470878279 (cloth) | ||
| 020 | |z 9781118274378 (e-book) | ||
| 035 | |a (CaPaEBR)ebr10580300 | ||
| 035 | |a (OCoLC)802068199 | ||
| 040 | |a CaPaEBR |c CaPaEBR | ||
| 050 | 1 | 4 | |a RS100 |b .D78 2012eb |
| 082 | 0 | 4 | |a 338.4/76151 |2 23 |
| 245 | 0 | 0 | |a Drug repositioning |h [electronic resource] : |b bringing new life to shelved assets and existing drugs / |c edited by Michael J. Barratt, Donald E. Frail. |
| 260 | |a Hoboken : |b John Wiley & Sons, |c c2012. | ||
| 300 | |a xx, 477 p. : |b ill. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Drug repositioning : the business case and current strategies to repurpose shelved candidates and marketed drugs / John Arrowsmith and Richard Harrison -- Opportunities and challenges associated with developing additional indications for clinical development candidates and marketed drugs / Donald Frail and Michael Barratt -- Clinical and operational considerations in repositioning marketed drugs and drug candidates / Damian O'Connell, David Sequeira, and Maria Miller -- Regulatory considerations and strategies for drug repositioning / Ken Phelps -- Computational and bioinformatic strategies for drug repositioning / Richard Mazzarella and Craig Webb -- Mining scientific and clinical databases to identify novel uses for existing drugs / Christos Andronis ... [et al.] -- Predicting the polypharmacology of drugs : identifying new uses through chemoinformatics, structural informatics and molecular modeling based approaches / Li Xie ... [et al.] -- Systematic phenotypic screening for novel synergistic combinations: a new paradigm for repositioning existing drugs / Margaret Lee -- Phenotypic in vivo screening to identify new, unpredicted indications for existing drugs and drug candidates / Michael Saporito, Christopher Lipinski, and Andrew Reaume -- Old drugs yield new discoveries : examples from the prodrug, chiral switch and site-selective deuteration strategies / Adam Morgan ... [et al.] -- Repurposing drugs for tropical diseases : case studies and open-source screening initiatives / Curtis Chong -- Drug repositioning efforts by non-profit foundations -- Business development strategies in the repositioning industry / Aris Persidis and Elizabeth Stark -- A case study in drug repositioning : Sosei / Akinori Mochizuki and Makiko Aoyama. | |
| 533 | |a Electronic reproduction. |b Palo Alto, Calif. : |c ebrary, |d 2011. |n Available via World Wide Web. |n Access may be limited to ebrary affiliated libraries. | ||
| 650 | 0 | |a Pharmaceutical industry |x Economic aspects. | |
| 650 | 0 | |a Drugs |x Economic aspects. | |
| 655 | 7 | |a Electronic books. |2 local | |
| 700 | 1 | |a Barratt, Michael J. | |
| 700 | 1 | |a Frail, Donald. | |
| 710 | 2 | |a ebrary, Inc. | |
| 856 | 4 | 0 | |u http://site.ebrary.com/lib/daystar/Doc?id=10580300 |z An electronic book accessible through the World Wide Web; click to view |
| 908 | |a 170314 | ||
| 942 | 0 | 0 | |c EB |
| 999 | |c 141507 |d 141507 | ||