Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry /
Saved in:
| Main Author: | |
|---|---|
| Corporate Author: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken, N.J. :
Wiley,
c2011.
|
| Subjects: | |
| Online Access: | An electronic book accessible through the World Wide Web; click to view |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000nam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | 0000148430 | ||
| 005 | 20171002062140.0 | ||
| 006 | m u | ||
| 007 | cr cn||||||||| | ||
| 008 | 110510s2011 njua sb 001 0 eng d | ||
| 010 | |z 2011019939 | ||
| 020 | |z 9780470484067 (cloth) | ||
| 020 | |z 9781118140383 (e-book) | ||
| 035 | |a (CaPaEBR)ebr10558150 | ||
| 035 | |a (OCoLC)794619804 | ||
| 040 | |a CaPaEBR |c CaPaEBR | ||
| 050 | 1 | 4 | |a RM301.5 |b .P48 2011eb |
| 082 | 0 | 4 | |a 615/.7 |2 23 |
| 100 | 1 | |a Peters, Sheila Annie. | |
| 245 | 1 | 0 | |a Physiologically-based pharmacokinetic (PBPK) modeling and simulations |h [electronic resource] : |b principles, methods, and applications in the pharmaceutical industry / |c Sheila Annie Peters. |
| 260 | |a Hoboken, N.J. : |b Wiley, |c c2011. | ||
| 300 | |a xvii, 430 p. : |b ill. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain. | |
| 533 | |a Electronic reproduction. |b Palo Alto, Calif. : |c ebrary, |d 2011. |n Available via World Wide Web. |n Access may be limited to ebrary affiliated libraries. | ||
| 650 | 0 | |a Pharmacokinetics |x Mathematical models. | |
| 650 | 0 | |a Drugs |x Design |x Mathematical models. | |
| 655 | 7 | |a Electronic books. |2 local | |
| 710 | 2 | |a ebrary, Inc. | |
| 856 | 4 | 0 | |u http://site.ebrary.com/lib/daystar/Doc?id=10558150 |z An electronic book accessible through the World Wide Web; click to view |
| 908 | |a 170314 | ||
| 942 | 0 | 0 | |c EB |
| 999 | |c 137579 |d 137579 | ||