Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry /

Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry /

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Bibliographic Details
Main Author: Peters, Sheila Annie
Corporate Author: ebrary, Inc
Format: Electronic eBook
Language:English
Published: Hoboken, N.J. : Wiley, c2011.
Subjects:
Pharmacokinetics > Mathematical models.
Drugs > Design > Mathematical models.
Electronic books.
Online Access:An electronic book accessible through the World Wide Web; click to view
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020 |z 9780470484067 (cloth) 
020 |z 9781118140383 (e-book) 
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100 1 |a Peters, Sheila Annie. 
245 1 0 |a Physiologically-based pharmacokinetic (PBPK) modeling and simulations  |h [electronic resource] :  |b principles, methods, and applications in the pharmaceutical industry /  |c Sheila Annie Peters. 
260 |a Hoboken, N.J. :  |b Wiley,  |c c2011. 
300 |a xvii, 430 p. :  |b ill. 
504 |a Includes bibliographical references and index. 
505 0 |a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain. 
533 |a Electronic reproduction.  |b Palo Alto, Calif. :  |c ebrary,  |d 2011.  |n Available via World Wide Web.  |n Access may be limited to ebrary affiliated libraries. 
650 0 |a Pharmacokinetics  |x Mathematical models. 
650 0 |a Drugs  |x Design  |x Mathematical models. 
655 7 |a Electronic books.  |2 local 
710 2 |a ebrary, Inc. 
856 4 0 |u http://site.ebrary.com/lib/daystar/Doc?id=10558150  |z An electronic book accessible through the World Wide Web; click to view 
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