Analysis of aggregates and particles in protein pharmaceuticals

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书目详细资料
企业作者: ebrary, Inc
其他作者: Mahler, Hanns-Christian, Jiskoot, Wim
格式: 电子 电子书
语言:英语
出版: Hoboken, N.J. : John Wiley & Sons, Inc., 2012.
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书本目录:
  • The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins
  • Separation based analytical methods for measuring protein aggregation
  • Laser light scattering-based techniques used for the characterization of protein therapeutics
  • Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals
  • Analytical methods to measure sub-visible particulates
  • Detection of visible particles in parenteral products
  • Characterization of aggregates and particles using emerging techniques
  • Ultraviolet absorption spectroscopy
  • Fluorescence spectroscopy to characterize protein aggregates and particles
  • Infrared spectroscopy to characterize protein aggregates
  • Raman microscopy for characterization of particles
  • Microscopic methods for particle characterization in protein pharmaceuticals
  • Comparison of methods for soluble aggregate detection and size characterization
  • Protein purification and its relation to protein aggregation and particles
  • Formulation development and its relation to protein aggregation and particles.