Plasmid biopharmaceuticals basics, applications, and manufacturing /
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| Главный автор: | |
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| Соавтор: | |
| Формат: | Электронный ресурс eКнига |
| Язык: | английский |
| Опубликовано: |
Hoboken, N.J. :
John Wiley & Sons,
c2011.
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| Предметы: | |
| Online-ссылка: | An electronic book accessible through the World Wide Web; click to view |
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Оглавление:
- Historical perspective
- Gene transfer with plasmid biopharmaceuticals
- Product and process development
- Structure
- Analytical characterization
- Delivery
- Ethical and safety issues
- Human and veterinary markets
- Human case studies : pandemic influenza and critical limb ischaemia
- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma
- GMPS and validation
- Product specifications and quality control
- Cell culture
- An overview of downstream processing
- Primary isolation
- Intermediate recovery
- Final purification
- Process synthesis
- Concluding remarks and outlook.