Ursula Klein (born 1952) is a German historian of science known for her cross-disciplinary work on the historical emergence of scientific and technological knowledge. She is a senior research scholar at the Max Planck Institute for the History of Science in Berlin, Germany. Her work has shown how experimentalists created specialised information technologies called "paper tools" to generate new knowledge systems. Her interpretation of such tools has been widely applied by historians, philosophers and sociologists of science and technology, and is seen as marking a foundational change in scientific reasoning and practice in the history of chemistry in the early 19th century. She holds that there is no clear dividing line between science and technology, oftentimes using the term "technoscience" to represent the historical interface between scientific reasoning and the material forms of knowledge produced within specialised industrial or medical settings. In 2016 she received the HIST Award for Outstanding Achievement in the History of Chemistry from the American Chemical Society.
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