11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet

The enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD) interconverts active glucocorticoids and their intrinsically inert 11-keto forms. The type 1 isozyme, 11β-HSD1, predominantly reactivates glucocorticoids in vivo and can also metabolise bile acids. 11β-HSD1-deficient mice show altered inflammator...

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Detaylı Bibliyografya
Asıl Yazarlar: Jethro, S Johnson, Opiyo, Monica N, Thomson, Marian, Karim, Gharbi, Andreas, Heger, Chapman, Karen E
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: The Journal of Endocrinology 2019
Konular:
Online Erişim:https://repository.daystar.ac.ke/handle/123456789/2965
Etiketler: Etiketle
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